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2,5-Dimethyl-celecoxib
100 INR
Product Details:
- Molecular Formula C18H16F3N3O2S
- Purity 98%
- Usage Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis.
- Molecular Weight 395.4 Grams (g)
- Physical Form Powder
- Solubility DMSO: 20 mg/mL
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2,5-Dimethyl-celecoxib Price And Quantity
- 1 Kilograms
- 100 INR
2,5-Dimethyl-celecoxib Product Specifications
- Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis.
- 395.4 Grams (g)
- C18H16F3N3O2S
- Powder
- 98%
- DMSO: 20 mg/mL
2,5-Dimethyl-celecoxib Trade Information
- Cash in Advance (CID) Cash Advance (CA)
- 500 Kilograms KG Per Month
- 2-8 Week
- Yes
- Sample costs shipping and taxes has to be paid by the buyer
- Carton and Poly Bag.
- Western Europe Central America Eastern Europe Africa Middle East South America Australia Asia North America
- All India
Product Description
2,5-
VETRANAL, analytical standard
Synonym: 2,5-
| grade | analytical standard |
| product line | VETRANAL |
| form | neat |
| application(s) | HPLC: suitable |
| gas chromatography (GC): suitable | |
| format | neat |
Biochem/physiol Actions
Celecoxib, and the inactive analog 2,5-dimethyl celecoxib both induce apoptosis in a many cancer cell lines by down-regulating the expression of survivin. This activiy is mediated via an AKT mediated pathway, and is unique to this class of cyclo-oxygenase inhibitors, as non-selective NSAIDs or other COX-2 specific inhibitors such as rofecoxib, do not effect survivin expression. Unlike celecoxib, 2,5-dimethyl celecoxib is devoid of any inhibitory activity against COX-2.
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