Synonym: 1,5-Dideoxy-1,5-imino-D-mannitol hydrochloride
Empirical Formula (Hill Notation): C6H13NO4 HCl
Molecular Weight: 199.63
CAS Number: 73465-43-7
solubility | H2O: soluble10 mg/mL |
Mode of action | enzyme | inhibits |
antibiotic activity spectrum | viruses |
storage temp. | 2-8C |
1, 5 mg in glass bottle
10 mg in poly bottle
1-Deoxymannojirimycin (DMM) hydrochloride is an inhibitor of N-linked glycosylation and has antiviral activity. Derivatives of deoxymannojirimycin may have anti-HIV activity. It has been used for treatment of T lymphocytes and to study its effect on allogeneic cytotoxic T lymphocytes (CTL)[1]. It is used for studies on Golgi-mediated glycoprotein processing.
1-Deoxymannojirimycin is a mannosidase I inhibitor, alters cell-surface complex carbohydrate structure as assayed by PHA-L binding, and increases high mannose structures as indicated by the increased Con-A binding[1].