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1,2-Bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid
Product Details:
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Product Description
1,2-Bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid
Synonym: BAPTA, Ethylenedioxybis(o-phenylenenitrilo)tetraacetic acid
Empirical Formula (Hill Notation): C22H24N2O10
Molecular Weight: 476.43
CAS Number: 85233-19-8
assay
|
| 96.0% (HPLC) |
| fluorescence | ex 251 nm; em 363 nm (pH 8.0 Highly selective calcium chelating reagent. Suitable for the spectrophotometric monitoring of Ca2+ levels) |
|
| ex 274 nm; em 363 nm (With Calcium) |
| storage temp. | 2-8°C |
Description
Application
Highly selective calcium chelating reagent. Suitable for the spectrophotometric monitoring of Ca2+ levels
1,2-Bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid was used for the spectrophotometric monitoring of Ca2+ levels. It may be used as chelator of cytosolic Ca²+ to investigate the effect of methoxychlor on cytosolic free Ca²+ concentrations and apoptosis in HA59T human hepatoma cells.[1]
General description
1,2-Bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid is a highly selective calcium chelating reagent.[4] Effect of microinjected calcium-loaded 1,2-bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid (CaBAPTA) on cell-to-cell diffusion of carboxyfluorescein has been studied in staminal hairs of Setcreasea purpurea.[3] It is reported to be a metabolite of 1,2-bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid tetra(acetoxymethyl ester) (BAPTA-AM) in rat urine.[2]
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