()-Verapamil hydrochloride

100 INR

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Product Details:

Molecular Formula C27H39ClN2O4
Melting Point 138-140°C
Molecular Weight 491.06
Usage Treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
Purity(%) 99%
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()-Verapamil hydrochloride Price And Quantity

Minimum Order Quantity 1 Kilograms
Price 100 INR

()-Verapamil hydrochloride Product Specifications

Usage Treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
Molecular Weight 491.06
Melting Point 138-140°C
Molecular Formula C27H39ClN2O4
Purity(%) 99%

()-Verapamil hydrochloride Trade Information

Payment Terms Cash in Advance (CID) Cash Advance (CA)
Supply Ability 500 Kilograms KG Per Month
Delivery Time 2-8 Week
Sample Available Yes
Sample Policy Sample costs shipping and taxes has to be paid by the buyer
Packaging Details Carton and Poly Bag.
Main Export Market(s) Western Europe Australia Eastern Europe Central America Africa Middle East South America Asia North America
Main Domestic Market All India

Product Description

(±)-Verapamil hydrochloride

Synonym: 5-[N-(3,4-Dimethoxyphenylethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile hydrochloride

Linear Formula: (CH₃O)₂C₆H₃CH₂CH₂N(CH₃)(CH₂)₃C[C₆H₃(OCH₃)₂][CH(CH₃)₂]CN · HCl
Molecular Weight: 491.06

CAS Number: 152-11-4

assay

	¥99% (titration)
form	powder
color	white
mp	142 °C (dec.)(lit.)
solubility	methanol: soluble50 mg/mL
	ethanol: soluble
originator	Pfizer
Gene Information	human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Description

Packaging

1, 5, 10 g in glass bottle

Biochem/physiol Actions

±₁-adrenoceptor antagonist; L-type calcium channel blocker. Blocks L-type Ca²⁺ channels in smooth and cardiac muscle, induces apoptosis of human primary and metastatic colon adenocarcinoma cells in vitro. Drug resistance reversal agent acting on Pgp, e.g. decrease renal tubule elimination of digoxin. Increases basal ATPase activity of Pgp. Substrate of Cyp3A4 and CYP2C6.

Features and Benefits

This compound is a featured product for ADME Tox research.

This compound is also offered as part of Sigmas Library of Pharmacologically Active Compounds (LOPAC), a biologically annotated collection of high-quality, ready-to-screen compounds.

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction.

This compound was developed by Pfizer.

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