()-Thalidomide

100 INR

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Product Details:

Molecular Formula C13H10N2O4
Melting Point 270 °C
Molecular Weight 258.23 Grams (g)
Chemical Name ()-Thalidomide
Purity(%) 99%
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()-Thalidomide Price And Quantity

Price 100 INR
Minimum Order Quantity 1 Kilograms

()-Thalidomide Product Specifications

Purity(%) 99%
Molecular Weight 258.23 Grams (g)
Melting Point 270 °C
Molecular Formula C13H10N2O4
Chemical Name ()-Thalidomide

()-Thalidomide Trade Information

Payment Terms Cash in Advance (CID) Cash Advance (CA)
Supply Ability 500 Kilograms KG Per Month
Delivery Time 2-8 Week
Sample Available Yes
Sample Policy Sample costs shipping and taxes has to be paid by the buyer
Packaging Details Carton and Poly Bag.
Main Export Market(s) Western Europe Australia Eastern Europe Central America Africa Middle East South America Asia North America
Main Domestic Market All India

Product Description

()-Thalidomide

Synonym: S()-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
- Empirical Formula (Hill Notation): C₁₃H₁₀N₂O₄
- Molecular Weight: 258.23
- CAS Number: 841-67-8

assay

	>98%
form	solid
optical activity	[]23/D 62.6°, c = 2 in DMF(lit.)
color	white
solubility	DMSO: soluble
	H₂O: insoluble
	ethanol: insoluble
originator	Celgene
Gene Information	human ... LITAF(9516), TNF(7124) mouse ... Nos2(18126) rat ... Nos1(24598)

Description

Biochem/physiol Actions

(-)-Thalidomide selectively inhibits biosynthesis of tumor necrosis factor (TNF-); inhibitor of angiogenesis. (S)-Thalidomide is a teratogenic enatiomer.

Packaging

10 mg in poly bottle

25, 100 mg in glass bottle

Preparation Note

(-)-Thalidomide is soluble in DMSO, but is insoluble in water and ethanol.

Application

Thalidomide has been used to study its teratogenic effects in chicken embryos and human embryonic cells. This study reported that thalidomide causes limb defects by stabilizing PTEN, inhibiting the expression of Akt and activating caspase-dependent apoptosis^[1]. Thalidomide has also been used for studying glutathione mediated teratogenic resistance in mouse embryos^[2].

Features and Benefits

This compound was developed by Celgene.

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()-Thalidomide

Product Details:

()-Thalidomide Price And Quantity

()-Thalidomide Product Specifications

()-Thalidomide Trade Information

Product Description

()-Thalidomide

Description

Biochem/physiol Actions

Packaging

Preparation Note

Application

Features and Benefits

Other Products in 'Biochemical & Reagents' category

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