(+)-Thalidomide

100 INR

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Product Details:

Melting Point 273-276°C
Density 1.6±0.1 g/cm3
Molecular Formula C13H10N2O4
Appearance White Solid
Molecular Weight 258.23
Chemical Name (+)-Thalidomide
Purity(%) 99%
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(+)-Thalidomide Price And Quantity

Minimum Order Quantity 1 Kilograms
Price 100 INR

(+)-Thalidomide Product Specifications

Chemical Name (+)-Thalidomide
Purity(%) 99%
Melting Point 273-276°C
Molecular Formula C13H10N2O4
Density 1.6±0.1 g/cm3
Molecular Weight 258.23
Appearance White Solid

(+)-Thalidomide Trade Information

Payment Terms Cash in Advance (CID) Cash Advance (CA)
Supply Ability 500 Kilograms KG Per Month
Delivery Time 2-8 Week
Sample Available Yes
Sample Policy Sample costs shipping and taxes has to be paid by the buyer
Packaging Details Carton and Poly Bag.
Main Export Market(s) Western Europe Central America Africa Middle East South America Australia Asia Eastern Europe North America
Main Domestic Market All India

Product Description

(+)-Thalidomide

Synonym: R-(+)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
- Empirical Formula (Hill Notation): C₁₃H₁₀N₂O₄
- Molecular Weight: 258.23
- CAS Number: 2614-06-4

assay

	98% (HPLC)
form	powder
color	white to beige
solubility	DMSO: soluble15 mg/mL, clear
originator	Celgene
storage temp.	room temp
Gene Information	human ... LITAF(9516), TNF(7124) mouse ... Nos2(18126) rat ... Nos1(24598)

Description

Biochem/physiol Actions

(-)-Thalidomide selectively inhibits biosynthesis of tumor necrosis factor (TNF-). (R)-Thalidomide is called "safe enantiomer", but it can be converted in the body to (S)-isomer.

Preparation Note

Thalidomide is soluble in DMSO at a concentration that is greater than or equal to 20 mg/ml. It is insoluble in ethanol and water.

Application

Thalidomide has been used to study its teratogenic effects in chicken embryos and human embryonic cells. This study reported that thalidomide causes limb defects by stabilizing PTEN, inhibiting the expression of Akt and activating caspase-dependent apoptosis^[1]. Thalidomide has also been used for studying glutathione mediated teratogenic resistance in mouse embryos^[2].

Features and Benefits

This compound was developed by Celgene.

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(+)-Thalidomide

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(+)-Thalidomide Price And Quantity

(+)-Thalidomide Product Specifications

(+)-Thalidomide Trade Information

Product Description

(+)-Thalidomide

Description

Biochem/physiol Actions

Preparation Note

Application

Features and Benefits

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