Synonym: (S)-(+)-Clopidogrel bisulfate, (S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogensulfate, Clopidogrel Bisulphate
Empirical Formula (Hill Notation): C16H16ClNO2S H2SO4
Molecular Weight: 419.90
CAS Number: 120202-66-6
assay
98% (HPLC) | |
form | powder |
optical activity | []/D +54 to +70, c = 0.5 in methanol |
color | white to tan |
solubility | DMSO: 20 mg/mL (warmed) |
originator | Bristol-Myers Squibb |
Sanofi Aventis | |
storage temp. | 2-8C |
(S)-(+)-Clopidogrel hydrogensulfate was used as standard in HPLC-MS/MS to detect clopidogrel and its thiol derivative in human plasma.
(S)-(+)-Clopidogrel hydrogen sulfate is an antithrombotic antiplatelet agent. It specifically and irreversibly inhibits the Purinoceptor P2Y12 subtype which inhibits ADP-induced platelet aggregation. (S)-(+)-Clopidogrel hydrogen sulfate is the active isomer.