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Product Description
(E)-Guggulsterone
Synonym: (17E)-Pregna-4,17(20)-diene-3,16-dione
Empirical Formula (Hill Notation): C21H28O2
Molecular Weight: 312.45
CAS Number: 39025-24-6
assay
95% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: soluble5 mg/mL
storage temp.
2-8C
Description
Biochem/physiol Actions
Naturally occuring bioactive plant sterol isolated from the gum resin of guggul (Commiphora wightii). Antihyperlipidemic. Induces the expression of human CYP3A.[]. Guggulsterone potently reverses multi-drug resistance in a number of human cancer cell lines, extending the efficacy of chemotherapy.