(6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride

Product Description

(6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride

 olubility  

Description

Biochem/physiol Actions

Natural cofactor for phenylalanine hydroxylase, tyrosine hydroxylase, tryptophan hydroxylase, and nitric oxide synthetase.

Packaging

5, 25, 100 mg in glass bottle

Preparation Note

(6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride ((6R)-BH₄ ) is soluble in oxygen free water at 19.60 - 20.40 mg/ml and yields a clear to slightly hazy, colorless to faint yellow solution.

Application

(6R)-BH₄ has been used as a buffer component for assaying tyrosine hydroxylase enzyme activity in mouse brain tissues³. (6R)-BH₄ has also been identified as an activator compound from a LOPAC library screen using a fluorogenic -glucosidase assay⁴.

Features and Benefits

This compound is also offered as part of Sigmas Library of Pharmacologically Active Compounds (LOPAC¹²⁸⁰), a biologically annotated collection of high-quality, ready-to-screen compounds.